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Razzaque MS, Wimalawansa SJ (2025) Minerals and human health: From deficiency to toxicity

Of concern, a non-statistically significant lower risk of hypertensive disease was found with zinc and selenium taken before pregnancy

However, it raises an interesting thought that maybe the benefit of SGLT-2 inhibitors on endothelial function, mediated by nitric oxide, may improve vasodilation of the pulmonary vasculature while reducing insulin resistance, elevated blood glucose, and obesity [105]